Common genetic variants in the repressive GATA-family transcription factor (TF) TRPS1 locus are associated with breast cancer risk, and luminal breast cancer cell lines TEASING BRUSH are particularly sensitive to TRPS1 knockout.We introduced an inducible degron tag into the native TRPS1 locus within a luminal breast cancer cell line to identify the
Associations between Traumatic Brain Injury, Drug Abuse, Alcohol Use, Adverse Childhood Events, and Aggression Levels in Individuals with Foster Care History
Nearly 50,000 Canadian children live in foster care.Compared with One-of-a-kind Hair-On Hides their peers, foster children experience greater independence and decreased guidance, predisposing them to harmful exposures such as traumatic brain injury (TBI), illicit drugs, and alcohol.Foster children also report a higher level of childhood abuse compa
A comprehensive analysis of erectile dysfunction prevalence and the impact of prostate conditions on ED among US adults: evidence from NHANES 2001-2004
BackgroundErectile dysfunction (ED) is characterized by the inability to achieve or maintain penile erection sufficient for intercourse.While previous research suggests a potential link between ED and prostate pathologies, the association between benign prostatic hyperplasia (BPH), prostatitis, prostatic cancer (PCa), and ED remains to be elucidate